Immunorestitution Diseases in Non-HIV Infected Patients

نویسندگان

  • V.C.C. Cheng
  • K. Y. Yuen
  • S.S.Y. Wong
  • P.C.Y. Woo
  • P. L. Ho
  • R. Lee
  • R.M.T. Chan
چکیده

The aim of the study is to assess the clinical spectrum of immunorestitution disease (IRD) in hospitalised patients over a 12-month period. In 9 of 18 patients who presented with clinical deterioration during reduction or cessation of immunosuppressants (n=6) or bone marrow engraftment (n=3), IRD cases included scabies infestation (n=1), gastric strongyloidiasis (n=1), hepatosplenic candidiasis (n=1), methicillin-resistant Staphylococcus aureus abscess formation (n=2), polyomavirus-related hemorrhagic cystitis (n=3), and influenza A pneumonitis (n=1). Immunopathological damage during withdrawal of immunosuppression is an incidental way to uncover an asymptomatic infectious disease. Serial monitoring of hematological and clinical profiles are essential in making a diagnosis of IRD.

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تاریخ انتشار 2008